ABSTRACT
The study was conducted a period of two years, 48 cases of newly diagnosed acute lymphoblastic leukemia were collected from the pediatric ward / oncology unit of Al- Kadlymia Teaching hospital together with 48 age and sex matched healthy children were taken as a control. The age of the patients range from 1.8-14 years. The majority were between [6-10] years 22 cases [45.85%]. 27cases [56.25%] were males and 2lcases [43.75%] females. Male: female ratio equal to 1.3:1. According to FAB morphological classification L2 constitute the majority ~29 cases [60.42%]. A white cell counts greater then 100.000/cm was encountered in the minority of cases, 5 cases only [10.41%], 3 of them were males and were more than 10 years of age. Mediastinal mass was found in 7 cases [1-4.58%] who were mainly males having FAB-L2. Immunofluorescence phenotyping of the peripheral blood lymphoblast has revealed that the patients had a higher mean percent of CD19, CDS then the control group, which is statistically highly significant [18.16+/- 5.47, 32.52+/-6.66] and [13.60+/-2.78, 19.91+/- 2.11] respectively. There was no much difference in the mean percent of CD3 and CD4 between the patients and the control group. [75.43.70, 43.2510.56] and [73.35 +/-11.55, 40.97 +/-7.77] respectively. In the patients group the mean percent of CDIO was [49.413+/-8.70], it was not done in the control group. According to this result, most of the patients had B-cell precursor leukemia, 30 cases [62.50% Followed by T-cell precursor leukemia, 18 cases [37.50 %]